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28-Nov-2017 04:26

This hypothesis has been based on the reported findings of gut microbial differences between healthy control subjects (HCs) and IBS patients, on findings in rodent models of IBS, and on the theoretical appeal of such a hypothesis to explain various clinical observations.

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In the absence of agreed upon biomarkers, the syndrome is defined by symptom criteria which include the presence of chronically recurrent abdominal pain associated with alterations in bowel habits [].A gastroenterologist or nurse practitioner obtained a medical history and physical exam to confirm the IBS diagnosis. With regard to IBS diagnostic subtypes, 11 subjects had IBS-constipation, 10 subjects had IBS-diarrhea, and 8 subjects had either alternating (1), mixed (5), or unspecified (2) bowel habits.

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